The journal · 28. oktober 2026 · 3 min lesing
The K-beauty ingredient everyone's talking about
Av Charlotte Nystuen
PDRN in skincare – that's why the ingredient is so popular in K-beauty
More bounce. More glow. Plumper-looking skin.
PDRN is one of the most exciting ingredients in Korean skincare right now. It has received a lot of attention for its potential in skin renewal, and is now found in everything from toners and cleansers to advanced face creams.
But what is PDRN, what benefits are associated with the ingredient, and what is the difference between salmon-based and vegan PDRN?
What is PDRN?
PDRN stands for polydeoxyribonucleotide and consists of DNA fragments. Traditional PDRN is often produced from purified DNA from salmon or trout.
What makes the ingredient so interesting is the research on its role in the skin's natural repair and renewal processes. Research on PDRN and polynucleotides has shown promising results in skin rejuvenation, skin texture, elasticity, and tissue repair.
In skincare, PDRN is particularly associated with skin renewal, elasticity, smoother skin texture, and plumper, more radiant skin.
When PDRN is combined with moisturizing ingredients such as hyaluronic acid, glycerin, and panthenol, the skin is also helped to retain moisture. This can provide an immediate plumping effect, making the skin look smoother, softer, and more supple.
Salmon PDRN vs. Vegan PDRN
Now there are both traditional salmon-based PDRN and vegan alternatives – two exciting directions in modern K-beauty.
Salmon PDRN
Salmon-based PDRN has a long history in research on tissue repair and aesthetic treatments. Clinical studies have shown promising results for certain PDRN and polynucleotide treatments, especially in skin rejuvenation and the skin's repair processes.
At Cama Reform you will find Dr. Reju-All Advanced PDRN Rejuvenating Cream, with 1,200 ppm pure salmon-based PDRN. The formula combines PDRN with niacinamide, panthenol, hyaluronic acid, and hydrolyzed collagen – ingredients that contribute to moisture and a smoother, plumper skin feel.
Vegan PDRN
Vegan PDRN is an alternative for those who wish to avoid animal-derived ingredients. The source and production method vary among manufacturers, and new fermentation-based methods open up more possibilities in skincare.
One example is Dr. Althea PDRN Reju 5000 Cream, with 5,000 ppm vegan, fermentation-based PDRN, along with centella asiatica, panthenol, and hyaluronic acid.
A higher ppm value does not automatically mean a better effect – the type of PDRN and the overall product matter.
Our PDRN favorites
Dr. Reju-All Advanced PDRN Rejuvenating Cream
A moisturizing gel cream with 1200 ppm salmon-based PDRN (99% purity), niacinamide, panthenol, and hyaluronic acid – for those who wish to explore PDRN in a nourishing routine focused on skin quality, moisture, and suppleness.
Dr. Althea PDRN Reju 5000 Cream
A vegan alternative with 5,000 ppm PDRN, centella asiatica, and hyaluronic acid. A nourishing cream for skin that needs moisture, comfort, and radiance.
Numbuzin No.9+ NAD+ PDRN Glow Boosting Toner
An essence-like toner that combines 1,000 ppm salmon-based PDRN with NAD+, peptides, and moisturizing ingredients. A glow-boosting step for skin that looks fresher and more hydrated.
Centellian24 Expert Madeca Cream Active Renew PDRN
A nourishing face cream with PDRN, developed with a focus on moisture and the skin barrier. A good alternative for those who prefer a richer cream in their routine. Contains 2000 ppm PDRN (Sodium DNA) and a TECA-PDRN™ complex with ingredients from multiple sources, including salmon, centella asiatica, rose, and houttuynia.
Anua PDRN Hyaluronic Acid Moisturizing Cleansing Foam
A cleansing foam with salmon-based PDRN and hyaluronic acid that cleanses the skin and contributes to a pleasant, moisturized skin feel. A great first step in a PDRN-inspired skincare routine.
Discover your PDRN favorites at Cama Reform.
Reform your skincare ritual.
